Responsibilities
Research Group Leader
Contact
Neurometabolism
Am Klopferspitz 18
D-82152 Martinsried
Email:
Angelika.Harbauer@bi.mpg.de
Website:
http://www.mpi-bi.de/Harbauer
Further Information
Keywords:
Mitochondria, RNA transport, local translation, neurodegeneration
Research methods:
live cell imaging, biochemistry, molecular biology
Selected publications:
Schmidt, O.*, Harbauer, A.B.*, Rao, S., Eyrich, B., Zahedi, R.P., Stojanovski, D., Schönfisch, B., Guiard, B., Sickmann, A., Pfanner, N., and Meisinger, C. (2011). Regulation of mitochondrial protein import by cytosolic kinases. Cell 144, 227-239. doi: 10.1016/j.cell.2010.12.015. (*equal contribution)
Harbauer, A.B., Opalińska, M., Herman, J.S., Rao, S., Guiard, B., Schmidt, O., Pfanner, N., and Meisinger, C. (2014) Cell cycle-dependent regulation of mitochondrial preprotein translocase. Science, 346(6213), 1109–13.doi: 10.1126/science.1261253.
Kravic B., Harbauer A.B., Romanello V., Simeone L., Vögtle F.-N., Kaiser T., Straubinger M., Huraskin D. Böttcher M., Cerqua C., Martin E. D., Poveda-Huertes D., Buttgereit A., Rabalski A. J., Heuss, D., Rudolf R., Friedrich, O., Litchfield D., Marber M., Salviati L., Mougiakakos D., Neuhuber W., Sandri M., Meisinger C., Hashemolhosseini S. (2018) In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy, 14(2), 311-335. doi: 10.1080/15548627.2017.1403716.
Harbauer A.B. (2017) Mitochondrial health maintenance in axons. Biochem. Soc. Trans. 45, 1045–1052 doi: 10.1042/BST20170023
Harbauer, A. B.; Hees, J. T.; Wanderoy, S.; Segura, I.; Gibbs, W.; Cheng, Y.; Ordonez, M.; Cai, Z.; Cartoni, R.; Ashrafi, G. et al. (2022) Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy. Neuron 110 (9), S. 1516 - 1531.e9 doi: 10.1016/j.neuron.2022.01.035